Abstract People have been looking for alternative energy sources because current sources may be depleted. Furthermore, it is critical to utilize available energy sources as effectively as possible. Turbulators are among the topics to consider when it comes to energy efficiency. In practice, turbulators are often used in exchangers to enhance heat transfer. Putting newly constructed turbulators in determined locations of the constant surface temperature heat exchanger, velocity, temperatures, pressure, and flow measurements have been performed in the inlet and outlet. In the case of using different numbers of turbulators, their placement in different locations, their arrangement at different distances, and their use at different Reynolds, the changes in pressure drop, Nusselt number, and friction factor were studied with the full factor experimental design. In addition, efficiency, exergy loss rate, and NTU efficiency parameters have been calculated, and the relationship between them has been presented graphically. When the test data were evaluated, it was seen that as the number of turbulators increased, the thermal efficiency, friction factor and pressure loss also increased. Using turbulators in different numbers, at different positions, at different distances, and with different Reynolds numbers, the effect ratio on the pressure loss, Nusselt number, and friction factor parameters was detected. In the analyses made, the most efficient parameters on heat transfer were determined, respectively, as Reynolds number (64.55%), position of turbulators (19.73%), distance between turbulators (6.09%), and number of turbulators (5.94%).